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Study Guides for IMM2022 at Monash University

Immunology in health and disease

IMM2022 Study Guide - Final Guide: Innate Lymphoid Cell, Adaptive Immune System, Bone Marrow
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Glossary Term Definition Innate immunity Protection against infection that relies on mechanisms that exist before infection, are capable of a rapid response to microb...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Fragment Crystallizable Region, Immunoglobulin G, Endothelium
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Isotype Function Production Structure Distribution Role in adaptive Serum conc and st...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Myc, Myeloma Protein, Cell Adhesion Molecule

Cancer Immunology VDJ recombination translocating the BCL2 *evidence for immune surveillance is on the from chrm 18 to the heavy chain locus on chrm 14 gives rise to a slow growing exam lymphoma. Cancer: is a disease of mu...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Poliomyelitis Eradication, Hpv Vaccines, Chickenpox

Vaccination Varicella (Chicken pox) MMR Passive: transfer of preformed antibodies or Small pox caused eradication in immune cells to a recipient. This can be done using an individuals own cells taking them 1979 expanding t...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Caseous Necrosis, Apoptosis, Metaplasia

Inflammatory disease induced by hydrolytic enzymes from Inflammation is trying to return to a surrounding (using inflammatory cells). homeostatic mechanism Caseous necrosis is a form of cell death in which the tissue maint...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Adaptive Immune System, Prostaglandin E2, Peptostreptococcus

Reproduction and the immune system Adaptive imm consists of CD4 and CD8 in MHC influences body odour attracted to regional LN found in sub epithelial LP and opposite MHC in a partner mucosal epithelium. IL17, Il23 and B de...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Segmented Filamentous Bacteria, Lacrimal Gland, Lamina Propria

Diet and the immune system IMM VS TOLERANCE Mucosal tissues include the urogenital tract, Protective immunity: invasive bacteria, kidney and lachrymal gland. viruses, toxins intestinal IgA, specific Ab present in serum loc...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Myasthenia Gravis, Vascular Smooth Muscle, Allergic Rhinitis

Hypersensitivity, allergy and autoimmunity injury. Also see opsonisation and Type 1: immediate hypersensitivity allergy phagocytosis 2. Ab mediated activation eg Ab against TSH R Ab stimulates Th2, IgE, eosinophils and mas...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Tlr 1, Tlr7, Tlr9

Infection and immunity 1 presentation. CTLs kill with perforin and 52 of death in low income countries are granzymes. caused by infectious diseases compared to 7 CTLs require help from TH1s (CD4). APC in high income countr...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Hematopoietic Stem Cell, Allotransplantation, Skin Grafting

Transplantation presence and specificity of HLA IgG Autograft =from one part of the body to antibodies to be defined HLA antibdoies bind to the bead, and another eg skin graft PElabelled secondary antibodies Isograft: betw...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Proinflammatory Cytokine, Acute-Phase Protein, Neuroinflammation

Mental health NFkB inflammation causes damage Neuropsychological disorders have high DALYs Note that when cytokines are given as part of MDD = major depression (more than two treatment eg IFNa for leukemia see weeks) incre...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Flow Cytometry, Cd19, B-Cell Linker

IMM2022: Immunodeficiency summary Looking at flow cytometry see lack of B notes cells Looking at flow cytometry again we can see FLOW CYTOMETRY progenitor cells then there is a block as we do Forward scatter: size (X axis)...

Science - Immunology
IMM2022
Kim Murphy
IMM2022 Study Guide - Final Guide: Polyethylene Glycol, Tumor Antigen, Rheumatoid Arthritis

Immunotherapy and alternative medicine UMABS = human made by replacing the Immunotherapy is a process or procedure mouse Ig gene locus with human Ig locus i.e made in a mouse using human genes. that is designed to target t...

Science - Immunology
IMM2022
Kim Murphy

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