PHY2011 Study Guide - Final Guide: Spermatogonium, Spermatogenesis, Spermatid
6 Jun 2018
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Lecture 4: Gametes
Lecture Objectives
1. Understand the processes involved in production of
spermatozoa
2. Understand the processes involved in production and
maturation of ova
Mitosis: Cell replication
• Normal cell division
• Mitosis is the nuclear division in all non- gamete cells in
which the number of chromosomes is maintained (from n to
n)
• interphase, prophase, metaphase, anaphase, telophase
Meiosis: Making gametes
• Gamete (sperm/ova) formation involves meiosis
• Meiosis is the nuclear division in the gonads in which
the number of chromosomes is halved (from 2n to n)
o Two consecutive cell divisions (meiosis I and
II) following one round of DNA replication
o When fertilization occurs, the normal diploid
chromosomal number is restored (in human, 2n
= 46)
o Produces four daughter cells
o Introduces genetic variation through random
alignment (muddles up chromosomes from two
different parents) and crossover (swapping of
chromosomal sections)
Meiosis – 1st Division
Document Summary
Lecture objectives: understand the processes involved in production of spermatozoa, understand the processes involved in production and maturation of ova. Mitosis: cell replication: normal cell division (cid:0, mitosis is the nuclear division in all non- gamete cells in which the number of chromosomes is maintained (from n to, (cid:0) interphase, prophase, metaphase, anaphase, telophase. Meiosis: making gametes: gamete (sperm/ova) formation involves meiosis (cid:0, meiosis is the nuclear division in the gonads in which the number of chromosomes is halved (from 2n to n, two consecutive cell divisions (meiosis i and. Ii) following one round of dna replication: when fertilization occurs, the normal diploid chromosomal number is restored (in human, 2n. Introduces genetic variation through random alignment (muddles up chromosomes from two different parents) and crossover (swapping of chromosomal sections) Spermatogonia: the founder stem cells, rest on the basement membrane, divide mitotically to produce more spermatogonia and primary spermatocytes.
