BCHM2072 Study Guide - Final Guide: Critical Role, Phosphorylase, Lipoprotein Lipase

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25 Jul 2018
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Metabolism is the chemical reactions of life- (cid:862)the g(cid:396)eat (cid:271)attle agai(cid:374)st e(cid:374)t(cid:396)op(cid:455)(cid:863). T(cid:449)o pa(cid:396)ts that a(cid:396)e coordinated must happen simultaneously: Anabolism is used to build and move things and consumes energy. Energy is liberated when things are broken down from building blocks to simple inorganics. Catabolism is used to break things down and releases energy. Anabolism and catabolism are coordinated by atp (adenosine triphosphate). The hydrolysis of the phosphates liberates the necessary energy. The energy from the is released as heat (which is undesirable) unless we can trap it to do something useful (unfavourable) such as anabolic reactions. Our body does not store much atp (cell [atp] ~ 5mm). Cellular [atp] must not dip below 3nm otherwise cell will die (this is the critical threshold). [atp] > [adp] > [amp] and all 3 must remain constant. Atp can o(cid:374)l(cid:455) (cid:271)e (cid:858)sto(cid:396)ed(cid:859) i(cid:374)di(cid:396)e(cid:272)tl(cid:455) as fuels su(cid:272)h as fats a(cid:374)d (cid:272)a(cid:396)(cid:271)oh(cid:455)d(cid:396)ates. The turnover of atp is massive; rate of.

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