EXSS1029 Study Guide - Final Guide: Endoplasmic Reticulum, Depolarization, Alpha Motor Neuron

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5. a. 1 describe the shape of the proteins tropomyosin and troponin, and the geometry of their arrangement on the thin filament. Actin forms the backbone of the thin filament. Tropomyosin and troponin are superimposed on the actin double helix. Tropomyosin molecules are joined end to end along the entire length of the thin filament. Forms a continuous thread running the entire length of every thin filament. Although connected to the thin filament, the threads are capable of small lateral movement. Found at intervals along the actin filament. Troponin and tropomyosin to the actin filament and controls its lateral movement. Can reversible bind ca2+ ions when they are present in the cytosol. Molecule can undergo a conformation change triggered by the binding of. 5. a. 2 describe the movements of tropomyosin, and explain the effect of these movements in terms of (i) blockage or exposure of cross-bridge binding sites, and (i) active force development.

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