EXSS1029 Study Guide - Final Guide: Myofilament, Sarcomere, Myocyte

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Myofilament = collective name for both thick and thin filaments. 400 actin molecules + 400 myosin molecules. 2. b. 2 describe in general terms the processes involved in thick filament assembly. Describe, sketch or identify the arrangement of myosin molecules in a thick filament seen in both longitudinal view and in cross section. Begins with anti-parallel packing of a set of myosin molecules. Followed by parallel packing of further molecules to this initial core. With further addition of molecules end to end, the polymer elongates in both directions. Thick filament is bipolar = the myosin molecules forming the lhs are facing in the opposite direction to those forming the rhs. Thick filament is cylindrical or rod shaped with heads facing in 6 directions. 2. b. 3 define a sarcomere and be able to describe its structure (either in 2 or 3 dimensions). Be able to sketch sarcomere structure and label its components in diagrams or photographs. (viewed either in longitudinal or cross section).