EXSS1029 Study Guide - Final Guide: Pamela Williams, Ankle, Sarcomere

• School: University of Sydney
• Department: Exercise and Sport Science
• Course: EXSS1029
• Professor: Professor

Document Summary

Exss1029 muscle mechanics and training: stretching and muscle passive stiffness and rom. Muscles show true lengthening by increasing the number of sarcomeres in series in their fibre. Can be measured in animals by removing the muscle in question and the fixing it a set length (average length is measured) A longitudinal section of muscle fibres are prepared for microscopy and average sarcomere spacing is then determined fibre length = sarcomere number x sarcomere spacing. Rearranging this equation to find the total number of sarcomeres in a series: Sarcomere number = fibre length sarcomere spacing. Dr pamela williams and geoffrey goldspink (1971, 1973) Using this method (the equations) increase in sarcomere number during maturation in mouse soleus is clearly shown. Fibres of soleus of a newborn mouse are around 600 sarcomeres long. As mouse matures to adulthood sarcomeres are continually added to fibre resulting in final adult fibre with >2000 sarcomeres end to end.