EXSS1029 Study Guide - Final Guide: Titin, Sarcomere, Lincoln Near-Earth Asteroid Research

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Exss1029 muscle mechanics and training: muscle length & passive force. 4. 1 sketch and explain in detail the shape of the relationship between active force and sarcomere length. Active force = force developed by the cross bridges transmitted to the z disc by the actin filament. The sarcomere shortens so that the thick and thin filaments overlap. As we increase the amount of overlap between thick and thin filaments, the total capacity of thick filaments increase in a linear manner until all five crossbridges can attach. 4. 2 explain the potential negative consequences of a complete loss of overlap between thick and thin filaments. Thin filament from one side of the sarcomere tends to override the thin filament from the opposite side. Pushes both thin filaments out of their optimal position. Decrease in developed force with further shortening. Or may be that increase in the spacing between the thick and thin filaments at short lengths may reduce crossbridge attachment.