IMED1002 Study Guide - Midterm Guide: Chromosome, Amide, Nitrogenous Base
LEARNING OUTCOMES LECTURES 9-10
- Nucleic acids functions:
➔ information storage = determine primary structure of protein
➔ Structural (rRNA) and functional (tRNA)
- Due to resonance in bases, it gives rise to a planar structure and the ability to absorb
UV light
Lecture 9:
- Nucleic acid: found in DNA/RNA and is a polymer of nucleotides
- Nucleotide: monomers of nucleic acid that includes phosphate group, sugar group and
nitrogenous base
- Nucleoside: sugar group and nitrogenous base (without phosphate group) = glycosidic bonds
- Nitrogenous base: heterocyclic aromatic structures, hydrophobic, exist as tautomers, bonds form
resonance = partial double bond
- Nitrogenous base: significance of double bonds results in bases being highly conjugated
compounds which causes e to be delocalized. Resonance in many atoms in the rings give partial
double bond character, giving stability, making them planar
- Pentose sugar: not planar, differ in OH (RNA) or H (DNA) on the second carbon, making DNA
stable and RNA unstable
- Phosphate: has net -2 charge because H+ dissociates when phosphate at physiological pH (7.4)
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Document Summary
Nucleic acid: found in dna/rna and is a polymer of nucleotides. Nucleotide: monomers of nucleic acid that includes phosphate group, sugar group and nitrogenous base. Nucleoside: sugar group and nitrogenous base (without phosphate group) = glycosidic bonds. Nitrogenous base: heterocyclic aromatic structures, hydrophobic, exist as tautomers, bonds form resonance = partial double bond. Nitrogenous base: significance of double bonds results in bases being highly conjugated compounds which causes e to be delocalized. Resonance in many atoms in the rings give partial double bond character, giving stability, making them planar. Pentose sugar: not planar, differ in oh (rna) or h (dna) on the second carbon, making dna stable and rna unstable. Phosphate: has net -2 charge because h+ dissociates when phosphate at physiological ph (7. 4) Information storage = determine primary structure of protein. Due to resonance in bases, it gives rise to a planar structure and the ability to absorb.
