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IMED2003 Study Guide - Midterm Guide: Randomized Controlled Trial, Internal ValidityPremium

2 pages95 viewsSpring 2018

Integrated Medical Sciences
Course Code
Kellie Bennett
Study Guide

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IMED2003: Revision 8 Notes
Different questions require different study designs
Most appropriate for assessing the effects of an intervention
But it says nothing about prognosis or prevalence
Cohort studies
Can answer a range of questions (depending on specific design)
Hierarchies of evidence for each question
Not all studies are the same
For some, their design specifically:
minimizes bias and confounding
Incorporating appropriate controls
Generating data of high validity, considered robust, high
quality research
Observational studies:
Absence of control or comparison groups weakens the strength of
observational studies
Placing them lower down in the hierarchy
Low quality research
The hierarchy is intuitive
For the most part accurate.
Evidence hierarchy is considered a continuum
The best evidence to use in decisions is the evidence highest in the
Evidence from a lower level should be used only if there is no good
randomised controlled trial to answer a particular clinical question.
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