IMED2003 Study Guide - Midterm Guide: Randomized Controlled Trial, Internal ValidityPremium
2 pages95 viewsSpring 2018
DepartmentIntegrated Medical Sciences
This preview shows half of the first page. to view the full 2 pages of the document.
IMED2003: Revision 8 Notes
Different questions require different study designs
○ Most appropriate for assessing the effects of an intervention
○ But it says nothing about prognosis or prevalence
● Cohort studies
○ Can answer a range of questions (depending on specific design)
Hierarchies of evidence for each question
● THINGS TO NOTE:
○ Not all studies are the same
■ For some, their design specifically:
● minimizes bias and confounding
● Incorporating appropriate controls
● Generating data of high validity, considered robust, high
○ Observational studies:
■ Absence of control or comparison groups weakens the strength of
■ Placing them lower down in the hierarchy
● → Low quality research
○ The hierarchy is intuitive
■ For the most part accurate.
○ Evidence hierarchy is considered a continuum
○ The best evidence to use in decisions is the evidence highest in the
○ Evidence from a lower level should be used only if there is no good
randomised controlled trial to answer a particular clinical question.
You're Reading a Preview
Unlock to view full version
Loved by over 2.2 million students
Over 90% improved by at least one letter grade.