PHAR1101 Study Guide - Quiz Guide: Ascanio Sobrero, Therapeutic Goods Administration, Penicillin

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1. Resistance to penicillin is conferred by bacterial enzymes that attack which of the
following structural components of the penicillin molecule?
oBeta lactam ring
1. Phocomelia describes which of the following deleterious outcomes seen in
thalidomide-poisoned offspring?
oLimb growth reduction
1. Each of these is a hallmark of the Metabolic Syndrome except one – which is it?
oInsulin hypersensitivity
1. In 1847, the Italian chemist Ascanio Sobrero invented nitroglycerin by reacting which
of the following chemicals together?
oGlycerol, nitric acid, sulphuric acid
1. Complimentary medicines are monitored by the Therapeutic Goods Administration
because:
oIt is part of its role in assuring their safety and effectiveness;
1. Which of these key scientists in the history of penicillin was born in Adelaide, South
Australia?
oHoward Florey
1. Which of the following was NOT a major factor contributing to limitations in the
effectiveness of synthetic antibiotics such as Salvarsan or “sulfa drugs” such as Prontosil?
oThey worked well in microbe-infected animals but not initially in humans
1. Which of the following symptoms was associated with so-called “Monday Disease”
which afflicted workers in TNT munitions factories?
o Headaches
1. Each of the following are considered “lifestyle diseases of affluence” except one –
which is it?
1. Which of the following CD proteins interacts with glycoprotein-120 on the HIV
particle during retroviral infection of T-helper cells?
oCd4
1. Which of the following describes the narrowing of arteries caused by the
deposition of fatty plaques?
oAtherosclerosis
1. The first anti-HIV drug used in humans belonged to which of these classes?
oReverse Transcriptase inhibitors
1. An individual with a body mass index (BMI) of 31.5 would be assigned to which of
the following groups?
oObese
1. Which of these species is most sensitive to the prenatal toxicity of thalidomide?
oHumans
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Document Summary

Resistance to penicillin is conferred by bacterial enzymes that attack which of the following structural components of the penicillin molecule: beta lactam ring. Phocomelia describes which of the following deleterious outcomes seen in thalidomide-poisoned offspring: limb growth reduction. In 1847, the italian chemist ascanio sobrero invented nitroglycerin by reacting which of the following chemicals together: glycerol, nitric acid, sulphuric acid. Complimentary medicines are monitored by the therapeutic goods administration because: o. It is part of its role in assuring their safety and effectiveness; Which of these key scientists in the history of penicillin was born in adelaide, south. Which of the following was not a major factor contributing to limitations in the effectiveness of synthetic antibiotics such as salvarsan or sulfa drugs such as prontosil: they worked well in microbe-infected animals but not initially in humans. Which of the following cd proteins interacts with glycoprotein-120 on the hiv particle during retroviral infection of t-helper cells: cd4.

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