BIOL 3553 Study Guide - Comprehensive Final Exam Guide - Protein, Immunoglobulin G, Cytokine
Document Summary
Physical barriers colonized by commensal microorganisms protect against infection by pathogens: the outer parts of our body are parts where we would get a microbial infection. The innate immune response is important as a barrier: antimicrobial peptides are very small chains of amino acids and are really good at poking small holes in microbes, eventually killing them. Intracellular and extracellular pathogens require different types of immune response: the type of immune response activated depends on whether it is an extra or intracellular pathogen. Most types of pathogens that would be inside the cell are viruses, there are some bacteria that are intracellulr but most bacteria are extracellular. Inflammatory cytokines recruit neutrophils from the blood to the infected tissue. Neutrophils are potent killers of pathogens and are themselves programmed to die. Opsonizaiton: il interleukin a protein that interacts with one leukocyte and has an affect on another leukocyte.
