BIOL 3P28 Study Guide - Midterm Guide: Metaphase, Oogenesis, Rhob
6 Dec 2013
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Biol 3p28 2nd midterm morphogenesis - formation of organized animal bodies. Morphogenesis results from a limited number of cell behaviors. Direction and # of cell divisions, shape changes, movement, growth, death, surface changes. Epithelial cells - form tubes and sheets while remaining adhered to one another. Mesenchymal cells - migrate individually, form extensive ecm that keep individual cells separate. Re-aggregation of cells & sorting out final positions reflect embryonic location cells have a different set of proteins in its cell membrane, these differences are responsible for forming the structure of the tissues and organs during development. Explain patterns of cell sorting based on thermodynamic principles (cells move to create tissue) Cells form a sorting hierarchy by differential surface tensions. Cells with greater surface tension sorted within cells that w/less surface tension (less adhesive outside) Surface tensions of individual germ layers are precisely those required for sorting pattern.
