NEUR 3304 Study Guide - Final Guide: Cortisol, Wild Type, Tryptophan

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Arc: works in opposition to leptin; concentrations are inversely correlated and tightly associated with regulation of energy balance, food intake, and body mass, plasma levels increased by stress. Ghsrs: antagonists also block stress induced weight gain and increased caloric intake, knockouts cannot defend adipose stores following stress. Questions: describe in detail three ways by which ghrelin and leptin afect the brain to modulate food intake. But when you stress them they go for carbs because it"s faster fuel: stress increases ghrelin for a long time, even after 3+ weeks post last stressor. Slow fuel: at the end, metabolically stressed animals gained weight in comparison to the non-stressed animals (this is alie"s research) First response to stress is to decrease body weight, but after time your physiological response is to ight back against it. These rats must then put on weight: recovery phase: undershoot phase of metabolic response.