MICI 4218 Midterm: MICI 4218 Midterm 1 Notes

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Clinical microbiology: a discipline that seeks to confirm the etiologic cause of infectious disease using a variety of laboratory techniques such as, culture, microscopy, ag detection, serology, molecular diagnostics, proteomics, epidemiology. Laboratory work-flow: collection transport/storage accessioning processing interpretation/identification susceptibility testing/molecular testing reporting/documentation. Transport: transport time to the laboratory, specimen type: swabs, urine, blood, stool, fluids, scrapings, transport media: cary blair transport media, saf (parasites): f for formalin, specimens for culture are never placed in formalin. Neutrophils are indicators of an immune response; therefore, the presence of neutrophils represent a good quality specimen and as well, the location of neutrophils represent the site of infection. Empiric therapy: therapy on the basis of a clinical educated guess in the absence of complete information, based on epidemiology (most probably etiologies) If an organism is subsequently identified, antimicrobial therapy should be modified to provide the best. Combination therapy: treatment where the patient is given two or more drugs for a single disease, advantages:

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