MICI 2100 Final: MICI Study notes

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Antony van leeuwenhoek was the dude who saw and described the wee animalcules first. First clinical advances: edward jenner gave the first form of live vaccine in an unethical experiment exposing a boy to cowpox by scratching him with a contaminated needle which resulted in a mild form of disease. This is the origin of the concept of immunity and host defence. Louis pasteur: disproved aristotle"s stupid idea of spontaneous generation by the life force by the swan neck flask experiment. Koch"s postulates: to determine if an organism is the causative agent of a disease : The organism must constantly be associated with the disease. Suspected causal organism must be isolated from an infected individual and grown in pure culture. When a healthy susceptible host is inoculated with the pathogen from the pure culture, symptoms of the original disease must develop. The same pathogen most be re-isolated from the individual under experimental conditions.