BIOL 200 Study Guide - Final Guide: Dicer, Epigenetics, Rna Interference
22 Jun 2016
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Document Summary
Co-activators induces transcription by hyperacetylating the histone tails. Methylation and phosphorylation : both outcomes (can be active or inactive) Euchromatin thread like abundant in actively transcribing cells. Dna that is unwound to provide transcriptional template. Histone methyltransferases contribute to heterochromatin spreading one small region of condensed dna spreads itself out methylation of lysine (k) 9 inactivates. Hp1 binds and causes the condensation of the histones (methylation more and more histories) form large complexes of methylated histones. Antibody placed on agarose beads against chromatin marks this is how you gure out the sequence of the acetylated dna region. Barr bodies in females (in cats cause the mosaic structure) n-1 rule for how many x chromosomes to inactivate. Xist use xist non coding rna to deactivate an x chromosome. Binds and spreads on the x chromosome, represses this x chromosome expression. Epigenetic traits are transmitted independently of the dna sequence itself.
