BIOL 201 Study Guide - Midterm Guide: Profilin, Cofilin, Listeria
1 Apr 2018
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Calculations related to net growth rates, on-rate constants, off-rate constants, and critical concentrations of cytoskeletal polymers. (note: the rate constants for actin will be provided if necessary. Exam questions may include hypothetical polymers as well. ) Location and architecture of different actin networks. The cytoskeleton is the scaffold of the cell, determines shape. Very good tensile strength and moderate flexibility. Very good resistance to deformation forces, particularly bending and compression. Plays key roles in cell physiology and metabolism: sets up cell shape, structure, stability, mediates intracellular transport (ex: microtubule tracks, establishes spatial organization, basis of cell contraction and motility. Actin is an atpase that drives cell motility. Actin is one of the most significant components of your muscle. Part of the leading edge of cells (lamellipodia) and stress fibers: activator of myosin, cells have the ability to organize their actin. G-actin polymerizes into a two-stranded helical filament (f-actin)
