ANSC 323 Study Guide - Midterm Guide: Neuromuscular Junction, T-Tubule, Mecha

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Skeletal: striated, multinucleated cells (striped appearance), many mitochondria: attach to bones by tendons (conn. tissue, flexor: pull bone together. I band = thin (actin; anchored to z line: muscle fibres bundle -> fascicle -> covered by. Sliding mech (thin actin anchored at z, overlap w/ thick filaments myosin: myosin heads normally blocked by inhibitor tropomyosin (held in place on actin by. Ca channels, release sequestered ca in cell (major trigger) -> Relaxation: immediately after ca release; sr start pump ca back inside (active transport) Single nucleus per cell, some sr structure present, no t tubules: ca come from outside and from sr-> bind to calmodulin (not tropomyosin) (cid:862)(cid:271)alling up(cid:863) a(cid:272)tion -> shorten fibre, regulated by light myosin chains. Single unit: (visceral tissues; involuntary): gap junctions, forms large sheet -> contract as one unit (can be autorhythmic) ex: peristalsis. Multi unit: cells can act independently, nervous input (trigger each cell individually)

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