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BIOL 303 (14)


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Biology (Sci)
Course Code
BIOL 303
Laura Nilson

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BIOL 303 NOTES XENOPUS LAEVIS DORSAL/VENTRAL AXIS - benefits: egg big, develops quickly from fertilization to gastrulated egg and then tadpole, amphibian eggs easy to obtain - animal pole (dark pigment) o cortical rotation; individual blastomeres; asymmetrical division (smaller blastomeres at animal pole) o Blastocoel forms separating animal cap from cells beneath it – blastula - Gastrulation o Blastopore at grey crescent – dorsal mesoderm then epiboly (ectoderm moves down and surrounds vegetal region) o Dorsal lip of blastopore (somites and notochord) to ectopic site induces new axis therefore contains all necessary info to form a complete axis - Organizer: ability to become dorsal mesoderm; ability to dorsalize surrounding mesoderm; ability to dorsalize surrounding ectoderm into neural ectoderm; ability to initiate the movements of gastrulation and the ability to cause the neural plate to become the neural tube o Dorsal lip of blastopore = organizer - How mesoderm is induced in blastula o Animal cap + endoderm, get mesoderm
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