[MIMM 214] - Midterm Exam Guide - Everything you need to know! (47 pages long)

• School: McGill University
• Department: Microbiology & Immunology
• Course: MIMM 214
• Professor: Claire Trottier

Document Summary

Epithelial layer can be the surface of skin, gut respiratory tract lining etc. Different and markers are involved to trigger an immune response. Pattern recognition receptors (prrs) provide an initial discrimination between self and non-self. Prrs recognize broad categories of molecules that are commonly pathogens (pathogen associated molecular patterns they are not very specific lining, receptors found in. Pathogen detection leads to activation of sensor cells. This detection leads to dc activation which then bridges adaptive and immune response cells, response attraction infection vessels of vessels recruited hallmarks. Pattern recognition occurs at the local site of infection. Sensor cells (phagocytes like dendritic macrophages) induce an inflammatory by producing mediators such as chemokines and cytokines: chemokines are involved in cell. Recruitment of cells to site of: mediators have effect on endothelial cells lining blood leading to increased permeability so other immune cells can be. Redness, heat, swelling and pain are of inflammation.