PARA 438 Study Guide - Midterm Guide: Pattern Recognition Receptor, Lipoteichoic Acid, Hmgb1
23 Dec 2015
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Identify and briefly describe (provide examples) at least 4 classes of pamp. Pamps are recognized by receptors expressed on or in innate cells, or in the humoral response. May be recognized by non-leukocytes (eg epithelial cells). We don"t have the same classes of single-stranded rna as viruses, bacteria and parasites, we have mrna. Our mrna has methyl caps on the ends, which the viral ssrna is incapable of replicating. Cpg is a certain kind of nucleic acid sequence found in pathogens. Pilin and flagellin: proteins that are only expressed in bacteria, and are conserved on the outsides of the bacteria. Endotoxins on the outside of bacteria, like lps and. Specific sugar orientation, like mannan: identify and briefly describe (provide examples) at least 4 classes of damp. Our cells die cleanly, without releasing cell contents into the periphery. If cell contents can be found outside, floating around, is because of some sort of trauma and creates a danger signal.
