PHAR 201- Midterm Exam Guide - Comprehensive Notes for the exam ( 19 pages long!)
6 Oct 2017
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Phar 201 a father"s lasting influence on child health (lecture 8) Research theme: does a father"s lifestyle matter for healthy babies: use of rodent model + studying samples from men in northern canada, africa and. Greenland: there are many toxicants in the environment and due to weather patterns, they accumulate in the north and eventually make their way into the diet of men and women. Overkalix sweden: how much food a grandfather ate impacted health of future generations. Rats exposed to very high levels of a commonly used pesticide (used on things like grapes), affected the health of the next three generations. Linked to dna methylation changes in the sperm. First study to show that exposure could cause changes to an epigenetic mark within the germ line. Ng et al: male rats fed a high fat diet were overweight and effects such as altered metabolism passed to the offspring: phenotypic changes in the offspring observed in this case.
