PHGY 209 Study Guide - Final Guide: Severe Combined Immunodeficiency, Human Leukocyte Antigen, Epstein–Barr Virus

• School: McGill University
• Department: Physiology
• Course: PHGY 209
• Professor: Ann Wechsler

Document Summary

X y = from x to y. Bacterial infections are extracellular, so they require antibody response. High virulent bacteria = bacteria that actually cause some significant disease. Viral is intracellular (only discussed on last day) Smallpo(cid:454): ed(cid:449)a(cid:396)d je(cid:374)(cid:374)e(cid:396) (cid:374)oti(cid:272)ed (cid:373)ilk(cid:373)aids i(cid:374) (cid:272)o(cid:374)ta(cid:272)t (cid:449)ith (cid:448)a(cid:272)(cid:272)i(cid:374)ia, had ha(cid:374)d po(cid:272)k(cid:373)a(cid:396)ks a(cid:374)d did(cid:374)"t get smallpox. Leap of faith: inject vaccinia to protect people from smallpox. To get (cid:862)(cid:448)a(cid:272)(cid:272)i(cid:374)ated(cid:863) is the (cid:449)(cid:396)o(cid:374)g ph(cid:396)ase sa(cid:455) (cid:862)i(cid:373)(cid:373)u(cid:374)ized(cid:863). Immune sys organs: primary: make (cid:862)soldiers(cid:863, stem cells: yolk sac, fetal liver, bone marrow, thymus, secondary: send out soldiers lymph nodes, spleen, malt: mucosa-associated lymphoid tissue. Pathogen offense players tries to penetrate immune sys defense, cause sepsis (infection) Pathogen offense: bacteria, virus, fungi, protozoa, toxins, coagulases, and antigens (cid:862)antigen(cid:863), the agent of disease, can refer to: Hapten (if hapten is combined with carrier, it is an immunogen: ex. Allergen = type of immunogen: ex. pollen.