BIOCHEM 2EE3 Final: Biochem Notes
13 Sep 2018
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Document Summary
Chemical structures of nitrogenous bases, nucleosides, nucleotides, nucleic acids. Furanose form = cyclic form, so those are actually -d-ribofuranose and -d-2-deoxyribofuranose. Nucleoside 5"-triphosphates (amp) carry energy, while cyclic nucleotides are signals (camp, cgmp) Polynucleotides link 3" to 5" by phosphodiester on sugar ring. A-t = 1. 11 nm, h bonds 0. 28 & 0. 3nm. G-c = 1. 08nm, hbonds 2x 0. 29 & 0. 3nm. Ribosomal rna (rrna): basis of structure and fxn of ribosomes. Messenger rna (mrna): carries message for protein synthesis. Transfer rna (trna): carries amino acid for protein synthesis. Others microrna, short inhibitory rna (sirna): gene regulation small nuclear rna: gene splicing. Large intergenic non-coding rna (lincrna):idklol mrna in prokaryotes vs eukaryontes. Single mrna can contain genes for several polypeptides in pro. 2" oh in rna is prone to hydrolysis. Type ii recognize 4 or 6 bp that are palindromic. Dna is synthesized using terminating, marked bases as well as normal. Dnap adds primers until you hit a dideoxynucleotide.
