BIOLOGY 2B03- Final Exam Guide - Comprehensive Notes for the exam ( 103 pages long!)

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What are the functions of proteins: proteins do everything. Structural component of the cell, tubules, actins, and cytoskeleton elements. Form molecular motors: transport components around the cell. Important for the unique identity and function of membrane-bound organelles in the cell. Examples: glutamine synthetase: large donut-shape structure with an active domain in the middle. Immunoglobulin: y-shape; necessary for recognizing antigens, viruses and bacteria, in the cell and removing them: adenylate kinase: small, bent shape; shape essential for defining the substrate binding domain and the activity domain. Solubility: refers to a physical property of a molecule that can transiently interact with water through hydrogen bonding, thermodynamically favourable, a hydrophilic molecule: (or portion of a molecule) is one that is typically charge-polarized and. If hydrogens bonds can form with water = soluble. Found in the interior of cytosolic proteins and form a hydrophobic core hydrophobic amino acids accumulating on the exterior of the protein.

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