BIOLOGY 1P03 Study Guide - Thalamotomy, Globus Pallidus, Coenzyme Q10
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Parkinson’s Disease Treatments
-neuroprotective: theory based on concept that 3-4 thousand at-risk dopaminergic
neurons in human substantia nigra can be protected from the complex degenerative
process that causes premature cell death and depletion of dopamine.
-Mao B Inhibitiors: selegiline and rasagiline
-Dopamine agonists: pramipexole and ropinirole
-Bromocriptine + Mao B Inhibitor
-Deep Brain Stimulation
-Subthalamic nucleus versus globus pallidus DBS
-Thalamotomy and pallidotomy
-Risks and complications
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