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Midterm

BIOLOGY 2C03 Midterm: T3 v1


Department
Biology
Course Code
BIOLOGY 2C03
Professor
Kim Dej
Study Guide
Midterm

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NAME: ___________________STUDENT NUMBER:_____________________
Biology 2C03
Term Test #3
Instructors: Dr. Kimberley Dej, Ray Procwat
Date: Monday March 22, 2010
Time: 10:30 am to 11:20 am
Instructions:
1) This midterm test consists of 9 pages. Please ensure that all pages are present.
2) Print your name and student number at the top of each page. Also, print your name and student
number on the scantron card.
3) There are 20 multiple-choice questions (1 mark each). Please use the computer card to record your
multiple-choice answers. Any answers not indicated on the scantron card will not be graded. (20 marks
total)
4) There are 2 short-answer questions. Please answer these questions in the allotted space on this quiz.
(15 marks total).
5) The final grade is out of 35 marks.
6) The test is 50 minutes long.
7) Please hand in the test package and the scantron card at the end of the test. Removal of tests is
considered academic dishonesty.
Good luck!!
Biology 2CO3: Genetics Winter 2010 Page 1 of 9
Grade:
MCQ : /20
SA: /15
Final: /35

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NAME: ___________________STUDENT NUMBER:_____________________
Part A. 20 Multiple-choice questions: 1 mark each.
Please indicate your answers on the scantron card.
Questions 1 to 4. A black female cat (XbXb) and an orange male cat (XBY) were mated to each other and
produced a male cat that was calico.
1. What is the karyotype and genoytype of this cat with respect to the sex chromosomes only?
a) XbXBXB
b) XbYB
c) XbXBXb
d) XbXBY
e) Xb
2. How many Barr Bodies would you see in this cat’s somatic cells?
a) none
b) one
c) two
d) three
e) four
3. Which sex chromosomes and genotypes did this male inherit from his father? (1 mark)
a) Xb
b) XbY
c) XBY
d) YB
e) XB
4. Male calico cats are rare. What mistake caused this to occur, when did it occur and in which parent?
a) Nondisjunction in meiosis I of the mother
b) Nondisjunction in meiosis II of the father
c) Nondisjunction in meiosis I of the father
d) Nondisjunction in meiosis II of the father
e) More than one of these above options is possible
5. What is the product of the Xist locus that is required for X-inactivation?
a) a protein that coats the active X-chromosome
b) a protein that coats the inactive X-chromosome
c) an RNA that coats the active X-chromosome
d) an RNA that coats the inactive X-chromosome
e) the product has not yet been characterized
Biology 2CO3: Genetics Winter 2010 Page 2 of 9

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NAME: ___________________STUDENT NUMBER:_____________________
6. In the following diagram, which is an example of a cis-acting sequence and which is an example of a
trans-acting factor?
cis-acting ; trans-acting
a) enhancer ; silencer
b) activator ; TFIID
c) TFIID ; promoter
d) silencer ; activator
e) activator ; enhancer
7. Gene silencing (preventing gene transcription):
a) involves changes in nucleotide sequence, C to G
b) may occur through the methylation of cytosines
c) may occur by histone acetylation in heterochromatin
d) involves gene splicing
e) both a and b
8. Which is an example of post-transcriptional processing that occurs during the synthesis of a mature
eukaryotic mRNA
a) removal of intervening sequences (introns)
b) DNA methylation
c) chromatin remodeling
d) histone acetylation
9. What would be the genotype of the four gametes produced by nondisjunction of the X chromosomes
at the second division in the formation of a spermatocyte in humans (note: nullo means a gamete with
no sex chromosomes).
a) X, X, Y, Y
b) XY, XY, nullo, nullo
c) Y, Y, nullo nullo
d) X, X, YY, nullo
e) XX, Y, Y, nullo
Biology 2CO3: Genetics Winter 2010 Page 3 of 9
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