[HTHSCI 1H06] - Final Exam Guide - Comprehensive Notes fot the exam (61 pages long!)

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Immunology 1- innate immunity: definition of immunity. Type of pathogen: bacteria (intercellular, viruses (all intracellular, fungi, extracellular parasites, the lymphatic system. Lymphatics (garbage dump for the tissue) drain the tissues of the body: return fluid, proteins, and cells to the blood via the thoracic duct, bring together the components of the immune system. Lymph nodes: important nexuses in the immune system. Primary lymphoid tissues: where cells develop, and are educated. Bone marrow (b and t cells)- b cells are educated here. Thymus (t- cells only)- t cells are educated here. Secondary lymphoid tissues: where immune components are brought together to mount a response. The immune system at a glance: levels of immunity. Intrinsic barriers: per-formed barriers to prevent invasion, ex. skin. Mechanical: expulsive force (coughing/sneezing/defecation/urination, ciliary beating (mucosa moving north and we swallow what was in our lungs and it gets killed off, tight junctions in the epithelium.

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