[HTHSCI 2H03] - Midterm Exam Guide - Comprehensive Notes for the exam (26 pages long!)

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 2H03
• Professor: Kirsten Culver

Document Summary

A condition that is characterized by the adrenal cortex ceasing to secrete endogenous glucocorticoids. This happens when a client is abruptly withdrawn from long-term glucocorticoid therapy. Prolonged glucocorticoid therapy provides negative feedback to the pituitary stop secreting acth. W/o acth, adrenal cortex shrinks, ceasing the secretion of endogenous glucocorticoids. Chronic corticosteroid insufficiency is treated with replacement therapy w/ glucocorticoids. Goal: achieve same physiological level of hormones in the blood if the glands were fxning properly. Corticosteroid implies that the drug has both glucocorticoid and mineralocorticoid activity. Cortisol, corticosterone, and cortisone are glucocorticoids secreted from When cortisol levels in the blood rise, negative feedback system is stimulated, signalling the hypothalamus and pituitary to shut off release of glucocorticoids thyroid hormone 2 hormones involved: thyroxine (t4, triiodothyronine (t3) Numbers on the t represent the number of iodine atoms in each molecule. By stimulating the enzymes involved with glucose oxidation. Increasing cellular metabolism causes thyroid hormone to increase body temperature.