HTHSCI 2HH3 Study Guide - Final Guide: Side Effects Of Penicillin, Dna Gyrase, Serum Sickness

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Document Summary

Irreversibly bind bacteria can produce bl penicillin-binding ring and deactivate bl , proteins preventing decrease binding affinity proper formation of to penicilins bc of altered bacterial cell wall. structure, decreased cell. Weakened wall inability permeability to contain osmotic pressure of cell cell rupture. Bactericidal fever, seizures, rash, anaphylaxis, hemolytic anemia, neutropenia, thrombocytopenia, gi (nausea, vomiting, diarrhea) Generation affects coverage and use gram +ve, increasing gram ve w subsequent generations (gen 1-4), oral anerobes broad spectrum: covers gram +ve, gram ve, oral and gut anaerobes. Serum troughs wall and prevents formation of the peptidoglycan layer in syndrome (flushing, need to be measured for erythema, pruritus), efficacy and safety leukopenia before 4th or 5th dose. Weakened cell wall is no longer able to contain osmotic pressure of cell, causing the cell to rupture. Modification of antibiotic nephrotoxicity, ototoxicity admin iv, peaks and. Treatment for serious synthesis by binding the by enzymes. Altered and vestibular toxicity troughs measured to infections.