HTHSCI 2C06 Study Guide - Final Guide: Chemical Synapse, Warfarin, Reuptake

• School: Mohawk College
• Department: Health Sciences
• Course: HTHSCI 2C06
• Professor: Ruth Hannon

Document Summary

Most psychiatric disorders are thought to be associated with excessive cns stimulation. Number or sensitivity of excitatory receptors. Number or sensitivity of inhibitory receptors. Responsible for maintaining emotional tone (mood, arousal, wakefulness and reward) In noradrenergic activity => seen in people with depression. In noradrenergic activity => responsible for manic symptoms seen in bipolar disorder. Maintains sleep-wake cycle, emotional tone and sensory perceptions (i. e pain) In serotonergic activity => depression and anxiety. Important dopamine tracts: nigrostriatal tract (substantia nigra striatum, tuberoinfundibular tract (hypothalamus pituitary, mesolimbic tract (vta limbic system, mesocortical tract (vta prefrontal cortex) Hyperprolactinemia (excess prolactin; hormone responsible for milk production) Projections from substantia nigra (pars compacta) to striatum (caudate and putamen) Hypothalamus (arcuate and periventricula r nuclei) to infundibular region (median eminence) Projections from the ventral tegmental area (vta) to the nucleus accumbens. Projections from the vta to the prefrontal cortex (pfc) Dopamine is released into the portal circulation connecting the median eminence with the anterior pituitary gland.