HTHSCI 2HH3- Final Exam Guide - Comprehensive Notes for the exam ( 27 pages long!)

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Damage to cns can lead to deafness, blindness, learning disabilities, paralysis or even death. Cns infections require early diagnosis, ct scans, mris, and lumbar punctures are key to making diagnosis. Ct scans: uses x-rays to produce images, good for imaging dense tissue such as bone. Mris: uses non-ionizing radio frequency signals to acquire its images, best for non-calcified tissues. Choice of pharm treatment depends on suspected pathogen & presence of blood brain barrier. Blood brain barrier: membrane that controls the passage of substances from blood into cns, it is lipophilic. Prevents certain antimicrobial drugs from penetrating the cns - ultimately limiting the types of drugs that may be used. Purple rash can be indicative of dic (caused by abnormally sustained production of thrombin). This is highly relevant in ppl with sepsis. Difficulty turning head horizontally is a positive sign of the jolt accentuation of headache test.

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