ISCI 1A24 Study Guide - Final Guide: Calorie Restriction, Telomere, Aneuploidy
24 Mar 2018
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Document Summary
Stem cells divide throughout our lifetime renewing our muscles, bone, liver and blood vessels and replacing our skin and blood cells that turn over rapidly. The cells that we have right now are not the cells we were born with, there was a turnove of cells - causing them to become differentiated from stem cells. Totipotent - can become everything in the human body. Cells become senescent after they have divided a certain number of times: replicative senescence. Hay flick limit: human cells possess limited replicative potential when grown in culture. A cell that is obtained from an organism. Finite time they can be kept in a culture. When they cannot replicate anymore, they remain in this state one year before death occurs. Replicative senescence = decline cell replacement and tissue repair (organismal aging) Size expansion, prominent golgi, enlarged nuclei and vacuolated cytoplasm nover. Size expansion, prominent golgi, enlarged nuclei and vacuolated cytoplasm.
