LIFESCI 2A03 Study Guide - Midterm Guide: Embryonic Stem Cell, Ernest Mcculloch, Asymmetric Cell Division
4 Nov 2018
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Document Summary
Stem cells discovery first identification of stem cells in 1963. Jim till and ernest mcculloch prove the existence of stem cells demonstrated that these cells were capable of self-renewal. Symmetric self-renewal (symmetric division): will increase the stem cell pool. Asymmetric division: maintains the stem cell pool, produces specialized cells to form and maintain tissues. Symmetric differentiation (symmetric division): reduces stem cell pool, produces specialized cell to form and maintain tissues. Cell potency is the ability of a cell to differentiate into other cell types. Totipotent: can give rise to all cell types in a body including extra embryonic tissue (i. e. placenta) ex. a zygote. Pluripotent: can give rise to all of the cell types that make up the body everything by extra embryonic. Multipotent: can develop into more than one cell type (but not all types) Unipotent: can give rise to new cells of a single, specific cell type or lineage differentiation ability decreased.
