LIFESCI 2N03 Study Guide - Final Guide: Frederick Sanger, Alpha Helix, Peptide Bond
Document Summary
Protein - greek derivative - protos = of prime importance. 2nd most abundant in plants and animals (first being water) Animal and plant based foods are a source. Proteins are made up of long amino acid(aa) chains. Conditionally essential - need an essential aa to make these aa. It is the side chains that make the aas unique. Proteins form in hierarchy of structures (least complex to more complex) Primary structure is cross-linking that occurs due to disulfide bridges. Alpha helix hydrogen bonds between nh and co dbonds. Albumin - major blood protein that carries fatty acids. Nonpolar on the inside, polar on the outside (cell membrane proteins) Each chain is referred to as a subunit. Hemoglobin, 2 subunits of 1 type alpha unit, and 2 subunits of another beta unit. Protein denaturation - loss of protein shape (normal function) Protein denaturation - loss of protein shape (normal function) ph, heat, alcohol, oxidation, mechanical agitation.