PSYCH 2NF3 Study Guide - Midterm Guide: Pineal Gland, Henry Molaison, Temporal Lobe
3 Apr 2018
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Guest speaker: intra-cortical mr signal as biomarker for pathology. Imaging the brain: mri: measures water-proton properties (hydrogen atoms), whole brain analysis, large variation in population, in vivo imaging, can see structural changes in volume (cortical thickness, healthy aging: myelin should increase into middle adulthood then taper off. Surface registration: provides cortical alignment compared to volume, can compare maps of brains, young brains have well defined pattern across depths. Intra-cortical signal can track aging and disease progression, help determine tissue composition. Bipolar disorder: decrease in cortical ogliodendrocytes, deficits in myelin development and in motor regions. Hu(cid:374)ti(cid:374)gto(cid:374)"s disease: single gene mutation, increase in glial density in cortex, cortex thickness decrease. Speech not localized to one part of brain it"s a (cid:272)ir(cid:272)uit. History: description of symptoms of person out of touch with reality as early as 1400bc changes with knowledge, memory, behaviour, control, sensations, delusions, irrational thoughts, greek physician aretaeus 2ad; e. p.
