BIOL 4010 Study Guide - Midterm Guide: Movement Protein, Tectivirus, Necrosis

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Protein coded by phage (c1) which binds to operator regions on genome. When all 3 operator regions are bound, all 3 promoter regions are inhibited. Interactions between dimers on o1 and o2 increase binding strength. O3 has a lower affinity for c1 and will be unbound when concentrations of c1 decrease. When o3 is unoccupied prm become active and c1 transcription increases, replacing the c1 on. Only high rate of c1 loss leads to expression of lytic genes lambda induction - role of reca, steps involved. Reca is normally a dna recombination enzyme but in response to dna damage become a protease. Targets (cid:272)ellular repressors as (cid:449)ell as c1, (cid:272)lea(cid:448)ed c1 is i(cid:374)a(cid:272)ti(cid:448)ated a(cid:374)d (cid:272)a(cid:374)"t (cid:271)i(cid:374)d. Reca also removes lexa which allows expression of many dna damage genes removal of c1 allows early lytic genes (cro) to be expressed cro inhibits c1 transcription and turns on expression of lytic genes.