[BIOL 205] - Final Exam Guide - Ultimate 59 pages long Study Guide!

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Lecture 1 epigenetics- dna will become rna only when dna is modified (methylated tags) 1 reverse transcriptase converts rna back to dna some rna cannot translate into protein (no start/ stop site) Types of rna: micro rna (mirna)- short rna"s have emerged as a new means of diagnosing and treating disease. Block translation of specific mrna into protein. 1 mirna can regulate a single gene or multiple gene networks form into hairpins so it can fold in on itself initiate breakdown of normal mrna: gets cleaved into 21 nucleotides. 70-98% of all rna in genome: piwi rna nucleolus- just a clump of rna as it is being transcribed. Human genome project- suppose to take 30 years, took 7 years if we could sequence everyone"s genes, could tell you what mutations you have/ what illnesses you will get some polymorphisms were due to sequencing errors. Sequence is like a basic script, everyone has different versions of same script.

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