BMED 271 Study Guide - Final Guide: Plasmodium, Disability-Adjusted Life Year, Sub-Saharan Africa

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Global burden of disease (gbd) is a measure of total health loss from all diseases of different populations: communicable diseases (50% of dalys in poor countries; 10% in developed countries): Hiv is the world"s leading infectious disease, having killed 40 million (3. 2 million were children). Hiv infects helper t cells (wbcs), causing acquired immunodeficiency syndrome (aids). Hiv is spread among people via bodily fluids (i. e. , semen, vaginal fluids, blood, breastmilk). Hiv is treated using antiretroviral therapy (art), but it does not cure the disease. The gbd for hiv is increasing in developing countries & decreasing in developed countries. Tuberculosis (tb) is a disease caused by the bacterium mycobacterium tuberculosis (mtb): Tuberculosis infects 30% of the world"s population; only 10% develop an active tb infection. Tb is treated with antibiotics, but drug resistance is made worse with non-compliance. The gbd for tb is decreasing, with 50% of all cases in south-east asia and western pacific.

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