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KNPE 255- Final Exam Guide - Comprehensive Notes for the exam ( 36 pages long!)
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36 Pages
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Spring 2018

Department
Kinesiology
Course Code
KNPE 255
Professor
Robert Ross
Study Guide
Final

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Queen's
KNPE 255
Final EXAM
STUDY GUIDE
Week 2 Lecture 3: Robert Ross et al.
Importance of Assessing Cardiorespiratory Fitness in Clinical Practice BOB ROSS
- Low levels of CRF associated with high risk of CVD, all-cause mortality, and mortality rates for
certain cancers
- CRF may be stronger predictor of mortality than smoking, hypertension, high cholesterol, and
T2D but not currently included in risk assessments
- Addition of CRF improves reclassification of risk for adverse outcomes
- CRF: ability to transport O2 to mito to perform physical work so it is functional capacity of
person and Reflects body health
o Half of variance in CRF due to heritable factors and their contribution to response of CRF
to PA is also half
o Measured directly with VO2 max or VO2 peak
- Age adjusted all-cause death rate decreases from low to moderate to high CRF in both sexes
Overview of CRF and Health Outcomes:
- CRF strong and independent marker of risk for CVD and All-cause mortality
- CRF stronger predictor of risk than other exercise test variables
- Each 1-MET higher CRF associated with sig. improvement in survival
- Strength of exercise capacity in predicting risk of mortality greater in F than M
Association BW CRF and Health Outcomes:
- Association bw CRF and health outcomes addressed in multiple populations
- Largest gains in survival noted when comparing lowest to next lowest CRF groups (health
benefits most noticeable at low end of CRF continuum)
- CRF has strong inverse association with incidence of all-cause mortality with lesser
improvements in health outcomes from moderate to high fitness groups
- High CRF levels not required to have sig. health benefits (< 5 METS = high risk) (>8-10 METS has
health protection)
- CRF can be used as preoperative predictor of surgical risk may because fitter patients can cope
with aerobic and myocardial demands caused by surgery
- Higher midlife CRF associated with lower risk of HF hospitalization in later life
- Strong inverse dose-response association between time spent walking and risk of stroke
independent of intensity and established/novel risk factors
Reclassification of CV Risk:
- Net reclassification improvement (NRI): indicates whether addition of biomarker correctly and
significantly alters risk classification (net change in risk bw those who do and do not experience
the event)
- Addition of CRF to risk scores improves risk predication and reclassification of risk for adverse
health outcomes beyond traditional scores
o Not included though because lack of evidence from RCTs
- Serial measures of CRF help with risk stratification because people whose CRF increases
between exams have lower risk than those whose CRF decreases
find more resources at oneclass.com
find more resources at oneclass.com
Week 2 Lecture 3: Robert Ross et al.
- Higher levels of CRF associated with reduced adverse health outcomes and chronic diseases in
additio to CVD (Deetia, Alzheier’s, Psyhologial stress, prediaetes, T2DM, ad Metabolic
Syndrome)
- Higher CRF also associated with lower risk of developing lung, breast and gastrointestinal
cancers and prevents disability later in life
- PA interventions targeting least fit individuals will have largest health benefit
Recommendations:
- Type: involve major muscle groups in continuous and rhythmic exercise
- Intensity: moderate and vigorous relative to capacity for healthy adults but light and moderate
for older and deconditioned adults
- Frequency: >5days of moderate, > 3 days of vigorous or combo for 3-5 days
- Time: 30-60 min of moderate and 20-60 min of vigorous per day of exercise but even >10 min is
good for inactive people
- Amount: 500-1000 METS-min/week recommended
- Pattern: one continuous sessions per day or multiple sessions per day greater than 10 mins
- Progression: increase volume by adjusting duration, frequency or intensity
find more resources at oneclass.com
find more resources at oneclass.com

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Description
[KNPE 255] Comprehensive spring guide including any lecture notes, textbook notes and exam guides.find more resources at oneclass.com Week 2 Lecture 3: Robert Ross et al. Importance of Assessing Cardiorespiratory Fitness in Clinical Practice BOB ROSS - Low levels of CRF associated with high risk of CVD, all-cause mortality, and mortality rates for certain cancers - CRF may be stronger predictor of mortality than smoking, hypertension, high cholesterol, and T2D but not currently included in risk assessments - Addition of CRF improves reclassification of risk for adverse outcomes - CRF: ability to transport O2 to mito to perform physical work so it is functional capacity of person and Reflects body health o Half of variance in CRF due to heritable factors and their contribution to response of CRF to PA is also half o Measured directly with VO2 max or VO2 peak - Age adjusted all-cause death rate decreases from low to moderate to high CRF in both sexes Overview of CRF and Health Outcomes: - CRF strong and independent marker of risk for CVD and All-cause mortality - CRF stronger predictor of risk than other exercise test variables - Each 1-MET higher CRF associated with sig. improvement in survival - Strength of exercise capacity in predicting risk of mortality greater in F than M Association BW CRF and Health Outcomes: - Association bw CRF and health outcomes addressed in multiple populations - Largest gains in survival noted when comparing lowest to next lowest CRF groups (health benefits most noticeable at low end of CRF continuum) - CRF has strong inverse association with incidence of all-cause mortality with lesser improvements in health outcomes from moderate to high fitness groups - High CRF levels not required to have sig. health benefits (< 5 METS = high risk) (>8-10 METS has health protection) - CRF can be used as preoperative predictor of surgical risk may because fitter patients can cope with aerobic and myocardial demands caused by surgery - Higher midlife CRF associated with lower risk of HF hospitalization in later life - Strong inverse dose-response association between time spent walking and risk of stroke independent of intensity and established/novel risk factors Reclassification of CV Risk: - Net reclassification improvement (NRI): indicates whether addition of biomarker correctly and significantly alters risk classification (net change in risk bw those who do and do not experience the event) - Addition of CRF to risk scores improves risk predication and reclassification of risk for adverse health outcomes beyond traditional scores o Not included though because lack of evidence from RCTs - Serial measures of CRF help with risk stratification because people whose CRF increases between exams have lower risk than those whose CRF decreases find more resources at oneclass.com
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