MICR 221 Study Guide - Final Guide: Double-Stranded Rna Viruses, Rna Virus, Viremia
Document Summary
The genomic segment doesn"t have a 5" cap so it can"t be recognized by a ribosome right away. Acts as a template to make (-) strands. (-) strand acts a template to make (+)mrna. Once inside cytoplasm, rna is converted to dsdna by reverse transcriptase. An exception in that it"s a (+) stranded rna virus that brings in its polymerase. Bound by integrase, and complex is transported into the nucleus --> integrase integrates virus genome into genome. Cellular rna polymerase ii is used (promotor on one end of the genome to makes a whole series of. A whole variety of splicing events can happen to yield different rna products to make differemt proteins. Small mrna piece is associated with membrane proteins in the er. Some rnas are full lengths that can be genomes that will be packaged. Polymerase that is encoded is the reverse transcritase. Rna-dependent (template is rna) rna polymerase (rna product)