PATH 310 Study Guide - Midterm Guide: Venous Thrombosis, Hemostasis, Tachycardia

• School: Queen's University
• Department: Pathology and Molecular Medicine
• Course: PATH 310
• Professor: Christine Hough

Document Summary

Normal process that stops bleeding after vessel injury with hemostatic plug. Pathological process with formation of a thrombus in an uninjured cell. Formation of a thrombus in a blood vessel. Dilation of blood vessels causing redness of the skin. Fatty streak- first lesion characterized by build up of lipids, cholesterol, calcium and cellular debris, endothelial dysfunction, vascular inflammation. Abnormally high levels of lipids in the body. Degeneration of vessel wall due to fat deposits. Pressure on heart due to fluid in pericardial sac. Highest risk before puberty, altered developmental expression of f9. As you age architecture gets worse (no genetic component) Mutation at transcription factor binding site/promoter, androgens from puberty can bind. Use anti-coagulants to prevent worsening not bust clots. Thrombolysis in severe cases, will break up good clots. Oral anticoagulants (vitamin k antagonists) interferes with pc and ps. No physical activity then allowed arrhythmia termination.