PHAR 100 Study Guide - Final Guide: Lovastatin, Antipsychotic, Antifolate

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Jeanne Mulder, William Racz

Document Summary

West/central africa: used in ordeal trials to identify sorcerers, healer gave poison to everyone; sorcerers did not vomit poison + * bold + italicize = drugs *bold = people/figure *^=increase *long/short-term effects (lte/ste) Lesson 1. 1: history of drug use and development. Influence of religion: medicine men were physicians/priests; religion & magic influenced therapy (eg. toxic substances were used to communicate with gods [eg. peyote cactus (mescaline, a hallucinogen)] Influence of poison: paracelsus (swiss physician) (cid:498)all substances are poison, right dose differentiates poison from remedy(cid:499) Ergotamine: causes vasoconstriction of blood vessels, reducing pulsation levels used for migraines. Ergonovine: contract uterus vessels to hasten delivery - too dangerous used to control post-birth bleeding. Influence of ancient civilizations: traditional belief: ancient herbs and animal materials are therapeutics and more effective than aspirin: ephedrine was isolated from ma huang and used to treat asthma and as a decongestant. Early greek medicine: theophrastus wrote a book that included opium.