PHGY 214 Study Guide - Final Guide: Activin And Inhibin, Hyperglycemia, Osteoblast

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Increase in pco2 co2 more soluble to oxygen, partial pressure is representative of the dissol(cid:448)ed gas, (cid:374)ot (cid:449)hat"s (cid:271)ou(cid:374)d to he(cid:373)oglo(cid:271)i(cid:374) si(cid:374)(cid:272)e it does (cid:374)ot (cid:272)o(cid:374)tri(cid:271)ute to pressure. Co2 will cross over into the brain stem, carbonic anhydrase activating chemoreceptors main drive to breathe, 65% of drive to breathe is by central chemoreceptor. Carotid chemoreceptors are the other main chemo sensory organs, sense chemical stimuli o2, desaturate less than 65 mmhg will activate these chemoreceptors. Conscious drive to breath will also contribute the drive to breathe (3 drives) 40% at rest partial pressure below 65 is when carotid bodies are activated and increase ventilation [ve=(tidal volume*frequency)] Hydrogen ion is charged so cannot cross a lipid membrane, co2 is the one being able to cross. Catalysis of co2 with water by carbonic anhydrase in brain ecf increase h+ = increase ventilation. Ventilation is l/min so there has to be some volume over time so (vol/f)

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