PHGY 350 Study Guide - Final Guide: Polycystic Ovary Syndrome, Thyroid Nodule, Acanthosis Nigricans

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Needs to be treated in first few weeks or else results in cretinism. Infection of adrenal glands (viral, tb, histoplasmosis) Deficiency in acth secretion (pituitary or hypothalamic pathology) Structural (absence of vas deferens, varicocele, undescended testes) Immunologic (antibodies against sperm, immune response to fetus) Secondary (cns/pituitary tumors, inhibition of gnrh, obstruction of outflow tract) Cytisis, bladder stones, kidney damage (due to urinary retension) Adenocarcinoma (surface epithelia) metastasize to lymph nodes, bone, liver, adrenal, lung. Fertility enhancement procedures (intrauterine insemination of concentrated sperm, Brca1 or brca2 mutation (x10 fold) ashkenazi jewish. Start: dysplasia of squamous epithelial cells @ columnar junction of external os. Pap smear: to detect dysplasia prior to carcinoma. Endometrial hyperplasia leading to dysplasia caused by unopposed stimulation. Aromatase inhibitor (2 adjuvant therapy) letrozole, arimidex. Intestinal inflammation se(cid:272)(cid:396)etio(cid:374) a(cid:271)so(cid:396)ptio(cid:374), i(cid:374)(cid:272)(cid:396). (cid:373)otilit(cid:455) = diarrhea. Biliary colic: blockage of bile outflow (transient or sustained) Colic-y pain, blocking somewhere from the secretory pathway from liver.

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