BME 804- Final Exam Guide - Comprehensive Notes for the exam ( 30 pages long!)

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Introduction to mems and their applications including medical applications proteomics dna biosensor/transducer biocompatibility etc. Micro total analysis system (utas) ; multiple chips perform all or part of a biochemical analysis. Lab-on-a-chip; subset of utas, devices that integrate lab functions on small-scale chip. Dna & protein microarrays; chips that are used to study interaction and activities of. *utas and lab-on-a-chip devices contain microchannels, microfilters, microvalvesetc: personalized medicine. Methods: topical, oral, injection, insertion and perfusion. Need to consider dose, frequency, duration, oscillatory behavior. Scaffolding devices, sensing and stimulation electrodes, electroactive (stimulated by electric field) polymers: minimally invasive procedures. Silicon microfabrication part i: mask creation silicon wafer preparation, thin-films deposition such as sio2 resist (positive or negative) application, uv exposure and development etching methods resist stripping inspection with profilometer. Microfabrication is the production of devices in the submicro to millimeter range. 2 types of techniques (differ in material and procedure: hard fabrication (traditional approach) Hard micromachining (materials: silicon, glass, ceramics: soft fabrication.

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