BMS 870- Final Exam Guide - Comprehensive Notes for the exam ( 55 pages long!)

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Neurons - wiring of ns; process info, sense enviro changes, comm changes to other neurons, command response. Glia - more numerous than neurons; insulate and nourish neurons; involved in guidance mechanism of neurons. Neurons discovered later than other cells due to limited tools. Studied tissue fixed in formaldehyde and sectioned in microtome. Nissl stain - only neurons; study of cytoarchitecture in the cns since differentiate neurons vs glia. Neurons - receive stimuli and transmit action potentials. Axons - output; hits synapse -> nt released. Silver = dye more sensitive than general dyes. Golgi believed neurons were continuous bc synapse very tiny. Neurons out in right angles - signalling outwards to cover max surface. Dendrites when contacting other neurons, there are nt receptors prese(cid:374)t to accept nt"s fro(cid:373) sy(cid:374)apse. Light microscope - limit of resolution of 100nm. Electron microscope - limit of resolution of 0. 1nm. Super resolution microscopes can detect distances of 20nm. Axon hillock decides to trigger ap or not.

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