HSM 330 Study Guide - Temporal Lobe, Prefrontal Cortex, Dentate Gyrus

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During past 2 centuries, study of l&m has been central to: philosophy, psycholo gy, biology. Society of neuroscience (1969) was founded before discovery of place cells, ltp. , animal model of human memory impairment, evidence of multiple memory systems, aplysia and drosophila b ecame productive simple systems for studying memory, development of neuroimaging technology. Most of what is now understood about l&m became known after the society was est ablished. Brenda miller (1957) described profound effects on memory of bilateral medial t emporal lobe resection performed to relieve epilepsy on hm. Hm showed profound forgetfulness, although his intellectual and perceptual func tions were largely intact. Only declarative memory was impaired in hm and other similar patients. Thus, memory is not a unitary faculty of the mind but is composed of multiple s ystems that have diff operating principles and diff neuroanatomy.

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