PAT 20A/B Study Guide - Final Guide: Chronic Obstructive Pulmonary Disease, Bronchitis, Elastic Fiber

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Document Summary

Group of disorders that cause chronic and recurrent obstruction of the pulmonary airways. Pt. will first complain of dyspnea on exertion and progress to interfering with adls and rest when disease is advanced can lead to: skeletal muscle dysfunction right sided hf. These people often display characteristics of both chronic bronchitis and emphysema. Patency of the bronchial structures ( chronic bronchitis) The gas-diffusing airspaces distal to the terminal bronchioles ( emphysema) People with copd can have features of both emphysema and chronic bronchitis. Genes: hereditary deficiency in a1-antitrypsin, result in early onset and severe lung injury with onset and severity worsened by smoking, less common. Exposure to particles: smoking= most common, occupational dusts organic and inorganic. Indoor air pollution from heating and cooking with biomass in poorly ventilated dwellings: outdoor air pollution. Inflammation and fibrosis of the bronchial wall. Impairs the expiratory flow rate which increases air trapping: predisposes to airway collapse.