[PLN 103] - Final Exam Guide - Everything you need to know! (86 pages long)

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First line of defense from things like the sun, environmental chemicals, microorganisms: largest system of the body (16% of body weight) 1. cutaneous membrane (skin: outer epidermis (superficial epithelium) b. inner dermis (connective tissues, hypodermis (loose connective tissue) The cutaneous membrane has many cells which help perform their function. Keratinocytes: main part of epidermis, made of keratin (dead cells, replaces every 4-6 weeks. Melanocytes: melanin synthesis (gives skin color) Langerhans: immune system, in bone marrow, surrounds keratinocytes to fight invaders. Merkel (tactile: btwn epidermis and dermis, sensory receptors for touch, accessory organs. Extends through epidermis to the surface of the skin like nails, hair, glands. The integumentary system is connected to the cardiovascular system (blood vessels in dermis: as well as nervous system (sensory receptors, central nervous system) Thin skin- most of your body (4 layers of keratinocytes) Thick skin- palms and soles of feet (5 layers of keratinocytes) Keratinization formation of dead cells filled with keratin (exposed skin)

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